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Original Article

A Study on Tuberculosis treatment outcome in known Diabetic Patients Treated under RNTCP in Bangalore

Ranganath TS1, Shivaraj BM 2

1  Professor and Head, 2Tutor cum PG, Department of Community Medicine, Bangalore Medical College and Research Institute, Bangalore

Corresponding author:

Dr. T.S. Ranganath Professor and Head Department of Community Medicine, Bangalore Medical College and Research Institute, Bangalore-560002, Email: tsranga1969@gmail.com, ranga_ts321@yahoo.co.in, 

Year: 2014, Volume: 4, Issue: 3, Page no. 152-154,
Views: 788, Downloads: 5
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Background: The rising prevalence of diabetes mellitus (DM) in countries with high burden of tuberculosis (TB) may adversely affect tuberculosis control. Revised National Tuberculosis Control Programme (RNTPC) prescribes the same treatment regimen for patients with tuberculosis and diabetes that is used for non-diabetics. Under the programme setting, there is a need for study on successful treatment outcome of Tuberculosis patients with known Diabetes Mellitus.

Objective: To analyze the Tuberculosis treatment outcome in patients with known Diabetes Mellitus treated under RNTCP setting in an urban area.

Methods: After cluster sampling among the 9 Tuberculosis Units in Bangalore 5 were chosen randomly. 75 TB-DM patients and 150 TB without Diabetes were enrolled into the study and followed up for their treatment outcome.

Results: Of the 75 TB-DM patients 72% were males and 28% were females. >90% of the patients were of age above 40 years. Overall treatment outcome was 81% and 87% among TB-DM and TB without DM respectively. It was not statistically significant (Fisher's exact test p=0.3256).

Conclusion: RNTCP's DOTS regimen holds good for TB patients with and without Diabetes Mellitus. The DM co-morbidity did not significantly change the TB treatment outcome. Hence the current DOTS regime under RNTCPcan be applied to the TB-DM co-morbid patients.

<p><strong>Background: </strong>The rising prevalence of diabetes mellitus (DM) in countries with high burden of tuberculosis (TB) may adversely affect tuberculosis control. Revised National Tuberculosis Control Programme (RNTPC) prescribes the same treatment regimen for patients with tuberculosis and diabetes that is used for non-diabetics. Under the programme setting, there is a need for study on successful treatment outcome of Tuberculosis patients with known Diabetes Mellitus.</p> <p><strong>Objective:</strong> To analyze the Tuberculosis treatment outcome in patients with known Diabetes Mellitus treated under RNTCP setting in an urban area.</p> <p><strong>Methods:</strong> After cluster sampling among the 9 Tuberculosis Units in Bangalore 5 were chosen randomly. 75 TB-DM patients and 150 TB without Diabetes were enrolled into the study and followed up for their treatment outcome.</p> <p><strong>Results:</strong> Of the 75 TB-DM patients 72% were males and 28% were females. &gt;90% of the patients were of age above 40 years. Overall treatment outcome was 81% and 87% among TB-DM and TB without DM respectively. It was not statistically significant (Fisher's exact test p=0.3256).</p> <p><strong>Conclusion: </strong>RNTCP's DOTS regimen holds good for TB patients with and without Diabetes Mellitus. The DM co-morbidity did not significantly change the TB treatment outcome. Hence the current DOTS regime under RNTCPcan be applied to the TB-DM co-morbid patients.</p>
Keywords
TB, DM, TB-DM, RNTCP, DOTS.
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