RGUHS Nat. J. Pub. Heal. Sci Vol: 14 Issue: 4 eISSN: pISSN
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Varadaraju DN, Satish Babu HV, Sastri S, Ananth G, Santosh KV, Patil SR
Address for correspondence:
Dr. D N Varadaraju, Department of Neurosurgery, Vydehi Institute of Medical Sciences and Research Center, #82, EPIPArea, Whitefield, Bengaluru 560066 varada_82@yahoo.co.in
Department of Neuro-Surgery, and Pathology, Vydehi Institute of Medical Sciences and Research Center, Bengaluru
Abstract
Non-Hodgkin's lymphoma (NHL) is an uncommon lesion involving the spinal epidural space, the usual age for presentation is fourth to fth decade of life. There is male preponderance (66-70%) with male: female ratio of 1.6:1. We present here a case of 48 years old female who presented with complaints of pain at upper back, and difculty in walking due to progressive spastic paraparesis and loss of bladder control. Based on MRI scan which revealed D4-D6 extradural lesion, patient underwent decompressive laminectomy and tumor excision. Histological examination revealed non-Hodgkin's Tcell rich B cell lymphoma following which a detailed workup for search of primary lesion was done which ultimately turned out to be negative. Patient was given adjuvant chemotherapy(R-CHOP). At follow up MRI spine showed no residual tumor at st the end of 1 year. It is concluded that spinal cord compression without any obvious primary lesion elsewhere, requires surgical decompression and tumor removal with adjuvant chemotherapy(R-CHOP) to recover neurological function and to help patient to lead a normal healthy life
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