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RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 4 eISSN:  pISSN

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Case Report

 Prathap Talwar1 , Ambarisha Bhandiwad 2

1 Assistant Professor, 2Professor, Dept of Obstetrics & Gynaecology, JSS Medical College, Mysore

Year: 2012, Volume: 2, Issue: 4, Page no. 241-242,
Views: 772, Downloads: 7
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CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Androgen insensitivity syndrome is a rare X-linked inherited form of male pseudohermaphroditism that occurs in phenotypically normal women with male karyotype. We report a 14-year-old girl who presented with a history of not attaining menarche and complaints of hoarseness of voice. Physical examination revealed prepubertal status of breast, clitoromegaly and blind vagina. Gonads were palpable bilaterally at inguinal region. Diagnostic laparoscopy revealed absence of uterus and adnexa. The karyotype of the patient was 46XY.

<p>Androgen insensitivity syndrome is a rare X-linked inherited form of male pseudohermaphroditism that occurs in phenotypically normal women with male karyotype. We report a 14-year-old girl who presented with a history of not attaining menarche and complaints of hoarseness of voice. Physical examination revealed prepubertal status of breast, clitoromegaly and blind vagina. Gonads were palpable bilaterally at inguinal region. Diagnostic laparoscopy revealed absence of uterus and adnexa. The karyotype of the patient was 46XY.</p>
Keywords
Androgen insensitivity syndrome, karyotype
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