Article
Cover
Journal Cover Page

RGUHS Nat. J. Pub. Heal. Sci Vol: 14  Issue: 4 eISSN:  pISSN

Article Submission Guidelines

Dear Authors,
We invite you to watch this comprehensive video guide on the process of submitting your article online. This video will provide you with step-by-step instructions to ensure a smooth and successful submission.
Thank you for your attention and cooperation.

Original Article

 Kulkarni ML1* , Kumar Saurabh2 , Sanjana Kalvehalli 3

1 Professor and Head, 2Resident, 3Medical Officer, Department of Paediatrics, JJM Medical College, Davangere

Year: 2012, Volume: 2, Issue: 2, Page no. 74-77,
Views: 756, Downloads: 4
Licensing Information:
CC BY NC 4.0 ICON
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0.
Abstract

Background and objective: To study the incidence of CNS manifestations in children with dengue, its spectrum of neurological manifestations and presence of dengue specific IgM antibodies in the CSF.

Method: Prospective study of all serum positive dengue patients (100 cases) admitted to the hospitals attached to J.J.M Medical College, Davangere from January 2009 to September 2010. Children who presented with neurological symptoms were separately grouped and CSF analysis, especially IgM, was done in them.

Result: The neurological incidence in our study was 40%. Seizures were present in 70% of cases and altered sensorium was present in 80% of cases. Papilloedema, and cranial nerve palsies were observed in 30% of cases and meningeal signs were present in 80% of cases. CSF protein was high in 80% of cases and pleocytosis was present in 80% of cases. CSF IgM was positive in 35% of cases. In our study and overall mortality was 4%.

Interpretations and Conclusion: Dengue fever encompasses an expanding clinical spectrum, not just restricted to WHO specified criteria for making a diagnosis other than DHF or DSS. It frequently causes encephalitis probably due to a direct neurotropic effect of dengue virus. 

<p><strong>Background and objective: </strong>To study the incidence of CNS manifestations in children with dengue, its spectrum of neurological manifestations and presence of dengue specific IgM antibodies in the CSF.</p> <p><strong>Method: </strong>Prospective study of all serum positive dengue patients (100 cases) admitted to the hospitals attached to J.J.M Medical College, Davangere from January 2009 to September 2010. Children who presented with neurological symptoms were separately grouped and CSF analysis, especially IgM, was done in them.</p> <p><strong>Result:</strong> The neurological incidence in our study was 40%. Seizures were present in 70% of cases and altered sensorium was present in 80% of cases. Papilloedema, and cranial nerve palsies were observed in 30% of cases and meningeal signs were present in 80% of cases. CSF protein was high in 80% of cases and pleocytosis was present in 80% of cases. CSF IgM was positive in 35% of cases. In our study and overall mortality was 4%.</p> <p><strong>Interpretations and Conclusion: </strong>Dengue fever encompasses an expanding clinical spectrum, not just restricted to WHO specified criteria for making a diagnosis other than DHF or DSS. It frequently causes encephalitis probably due to a direct neurotropic effect of dengue virus.&nbsp;</p>
Keywords
Dengue fever, encephalitis, encephalopathy, neurological manifestations of dengue
Downloads
  • 1
    FullTextPDF
Article

none

Supporting File
No Pictures
References

none

HealthMinds Logo
RGUHS Logo

© 2024 HealthMinds Consulting Pvt. Ltd. This copyright specifically applies to the website design, unless otherwise stated.

We use and utilize cookies and other similar technologies necessary to understand, optimize, and improve visitor's experience in our site. By continuing to use our site you agree to our Cookies, Privacy and Terms of Use Policies.