RGUHS Nat. J. Pub. Heal. Sci Vol: 14 Issue: 4 eISSN: pISSN
Dear Authors,
We invite you to watch this comprehensive video guide on the process of submitting your article online. This video will provide you with step-by-step instructions to ensure a smooth and successful submission.
Thank you for your attention and cooperation.
Harish S Permi1 , Patil C.N2 , Shetty J.P3 , Makannavar J.H4
1Assistant Professor, Department of Pathology,
2Assistant Professor, Department of Oncology 1,
3Professor and Head,
4Senior Professor
Department of Pathology, 1-Department of Oncology , K S Hegde Medical Academy of Nitte University, Deralakatte Mangalore, Karnataka, India, 575018.
Abstract
Epitheloid hemangioendothelioma is a rare tumor of vascular origin, which occurs at sites such as soft tissues, liver, or lung, and has a highly unpredictable malignant potential. It is an intermediate entity between well-differentiated hemangioma and angiosarcoma. Neoplastic cells express factor VIII related antigen, CD31 and CD34. Hepatic epitheloid hemangioendothelioma is a rare vascular tumor. The clinical course is unpredictable and different treatment modalities are offered depending on the patient’s conditions. Rosai-Dorfman disease, originally described as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Patients usually present with massive cervical lymphadenopathy. However other nodal sites (mediastinal and inguinal) are also frequently involved. The retro-peritoneum is an infrequent site of involvement.
We report a case of a 41 year old man presented with recurrent pain abdomen diagnosed as epitheloid hemangioendothelioma liver coexisting with retroperitoneal Rosai Dorfman disease. He was managed symptomatically without any modalities of treatment with regular follow up every month since one year. This case highlights the diagnostic dilemma of retroperitoneal Rosai Dorfman disease which mimicked metastasis from hepatic neoplasm and its rare association with epitheloid hemangioendothelioma liver
Keywords
Downloads
-
1FullTextPDF
Article
none
Supporting File
References
none